论文

•  Ye, S., Song, S., Liu, X., Luo, Y., Cai, S.* (2024) A small-molecule screen identifies novel aging modulators by targeting 5-HT/DA signaling pathway Aging Cell. : In Press.
•  Yao, L., Ruan, M., Ye, S., Cai,S.* (2023) DNA topoisomerase 2-associated proteins PATL1 and PATL2 regulate the biogenesis of hERG K+ channels. PNAS 120: e2206146120
•  Yuan, J., Chang, S., Yin,S., Liu, Z., Cheng, X., Liu, X., Jiang, Q., Gao, G., Lin, D., Kang, X., Ye, S., Chen, Z., Yin, J., Hao, P., Jiang, L.* &Cai,S.* (2020) Two conserved epigenetic regulators prevent healthy ageing Nature 10: 1038
•  Bai,X., Li,K.,Yao,L.,Kang,X.,Cai,S.* (2018) A forward genetic screen identifies chaperone CNX-1 as a conserved biogenesis regulator of ERG K+ channels J gen physiol 150: 1189-1201
•  Jiang,Q.,Li,K.,Lu,W.,Li,S.,Chen, X., Liu,X., Yuan,J.,Ding, Q.,Lan,F.,* ,Cai,S.,* (2018) Identification of small-molecule ion channel modulators in C. elegans channelopathy models Nat commun 9: 3941
•  Yin,J.,Gao,G.,Liu,X., Hao,Z.,Li,K.,Kang,X.,Li,H., Shan,Y.,Hu,W.,Li,H.,Cai,S.* (2018) Genetic variation in glia–neuron signalling modulates ageing rate Nature 551: 198–203
•  Li,K.,Jiang,Q.,Bai,X., Yang,Y.,Ruan,M.,Cai,S.* (2017) Tetrameric Assembly of K+ Channels Requires ER-Located Chaperone Proteins Mol cell 65: 52-65
•  Chen,X.,Ruan,M.,Cai,S.* (2015) KChIP-like auxiliary subunits of Kv4 channels regulate excitability of muscle cells and control male turning behavior during mating in Caenorhabditis elegans J neurosci 35: 1880-1891
•  Yin,J.,Liu,X.,Yuan,J.,Jiang,J.,and Cai,S.* (2014) Longevity manipulations differentially affect serotonin/dopamine level and behavioral deterioration in aging Caenorhabditis elegans J Neurosci 34: 3947-3958
•  Sesti,F.,Liu,S.,Cai,S. (2010) Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration? Trends cell biol 20: 45-51
•  Cai,S.*.,Wang,Y*.,Ki Ho Park*.,Tong,X., Pan,Z.,and Sesti ,F. (2009) Auto-phosphorylation of a voltage-gated K + channel controls non-associative learning Embo. J 28: 1601-1610
•  Tutak,W.,Ki-Ho, Park.,Fanchini,G.,Vasilov, A.,Cai,S., Partridge,N.,Sesti,F.,Chhowalla, M. (2009) Toxicity induced enhanced extracellular matrix production in osteoblastic cells cultured on single walled carbon nanotube networks. Nanotechnology 20: 25101
•  Cai,S.,Sesti ,F.* (2009) Oxidation of a K+ Channel causes progressive decline in sensory function during ageing Nat.neurosci 12: 611-617
•  Cai,S.,Sesti ,F.* (2007) A new mode of regulation of N-type inactivation in a Caenorhabditis elegans voltage-gated potassium channel J biol chem 282: 18597-18601
•  Cai,S.,Li,W.,Sesti ,F.* (2007) Multiple modes of A-type Potassium current regulation. Invited review Curr pharm frdign 13: 3178-3184
•  Hernandez,L.,K.H.Park.,Cai,S.,Qin, L.Partridge,N., Sesti,F. (2007) The antiproliferative role of ERG K+ channels in rat osteoblastic cells Cell biochem biophys 47: 199-208
•  Cai,S.,Hernandez L.,Wang Y.,Ki Ho Park.,Sesti F. (2005) MPS-1 is a K+channel b-subunit and a serine/threonine kinase Nat.neurosci 8: 1503-1509